Cosmetic Active System
Ergothioneine
Cellular Antioxidant Active for Premium Anti-Aging and Urban Defense Skincare
Ergothioneine (EGT) is a high-value antioxidant active used in advanced skincare formulations for environmental stress care, photoaging appearance support, redness-prone skin comfort, and healthy-looking radiance.
Premium cellular antioxidant story
Water-soluble active for serums
OEM/ODM formulation friendly
INCI
ergothioneine
CAS
497-30-3
Function
Antioxidant · Skin Conditioning
Recommended Dosage
0.01% – 0.5%
Shelf Life
24 Months
Product Overview
A Premium Antioxidant Active for Modern Skincare Development
Modern skincare consumers are looking for products that do more than basic moisturizing. Urban pollution, UV exposure, daily stress, and oxidative damage all contribute to dullness, fine-line appearance, uneven-looking tone, and loss of skin resilience. Ergothioneine gives formulators a premium active for anti-aging, urban defense, sensitive-skin comfort, and long-term skin quality positioning.
For OEM/ODM manufacturers and skincare brands, EGT is not only a functional antioxidant ingredient. Its OCTN1 / SLC22A4 cellular uptake narrative allows brands to build a more advanced “cellular antioxidant defense” concept for premium serums, creams, eye care, and day-care products.
01
Fast product positioning
Supports antioxidant, anti-aging, urban defense, and sensitive-skin concepts.
02
Formulation-friendly
Water-soluble profile makes it suitable for serums, essences, masks, and gel creams.
03
Procurement ready
COA, TDS, MSDS, formulation guide, sample, and quotation support available.
Function + Formulation Value
Key Benefits of Ergothioneine
01
Antioxidant Protection
Supports formulas targeting oxidative stress from UV exposure, pollution, and daily environmental stress.
02
Cellular Uptake Story
The OCTN1 / SLC22A4 narrative helps brands create differentiated cellular antioxidant positioning.
03
Photoaging Care
Suitable for daytime antioxidant products, after-sun products, and sunscreen-adjacent skincare systems.
04
Sensitive-Skin Comfort
Fits calming serums, recovery creams, sensitive-skin moisturizers, and gentle anti-aging formulas.
Market Applications
Suitable Product Concepts
Serum
Antioxidant Serum
For environmental stress, free-radical protection, dullness care, and cellular antioxidant positioning.
Anti-Aging
Anti-Aging Cream
For fine-line appearance, skin resilience, smoother texture, and healthier-looking firmness concepts.
Urban Defense
Day Care Products
Works with vitamin C derivatives, ferulic acid, tocopherol, niacinamide, and barrier-support ingredients.
Eye Care
Eye Serums & Creams
For fatigue appearance, dullness, fine-line appearance, and delicate-area antioxidant support.
Sensitive Care
Sensitive-Skin Moisturizer
Pairs well with panthenol, beta-glucan, ceramides, bisabolol, allantoin, and squalane.
After-Sun
After-Sun Care
Suitable for antioxidant and soothing support after environmental exposure, without SPF positioning.
Formulation Guide
How to Use Ergothioneine in Formulations
This section is designed for ODM/OEM and formulation teams. It gives practical use information before customers request documents or samples.
Get Formulation GuideUse Level
Typical reference range: 0.01% – 0.5%. Final dosage should be validated by formula design.
Solubility
Water soluble. Suitable for serums, essences, toners, masks, and gel creams.
Addition Phase
Add during cool-down phase when possible to reduce unnecessary thermal stress.
Compatible Actives
Vitamin C derivatives, niacinamide, ferulic acid, peptides, tocopherol, CoQ10, hyaluronic acid, and panthenol.
Stability Check
Validate pH drift, color, odor, assay retention, preservative compatibility, and packaging compatibility.
Packaging Suggestion
Airless, opaque, or UV-protective packaging may be considered for premium antioxidant products.
Technical Specifications
Product Technical Parameters
Parameter | Specification |
|---|---|
INCI Name | Ergothioneine |
Appearance | White to off-white crystalline powder |
Purity | 98% |
Recommended Dosage | 0.01% – 0.5% typical cosmetic reference range |
Solubility | Water soluble |
pH Stability | 5.0 – 8.0 |
Application | Antioxidant · Skin Conditioning |
Storage Condition | Store in a cool, dry place. Keep sealed and protected from light, heat, and moisture. |
Shelf Life | 24 months |
Why Choose NOYAIN®
Supply Support for EGT Projects
- High-purity cosmetic grade available for premium skincare projects
- COA, TDS, MSDS, regulatory statement, and formulation guide support
- Sample support for R&D teams, OEM/ODM projects, and distributor evaluation
- Batch quality consistency for long-term cooperation
- Technical communication for application selection and use-level evaluation
- Suitable for antioxidant, anti-aging, urban defense, and sensitive-skin concepts
Kind Tips
Formulation Precautions
Cool-Down Phase Addition
Add Ergothioneine during the cool-down phase when possible to reduce unnecessary thermal stress and help maintain ingredient stability.
Compatibility Validation
Validate compatibility with strong acids, high electrolytes, metal ions, highly oxidative ingredients, and complex botanical extracts before finalizing the formula.
Stability Testing
Confirm color, odor, pH drift, assay retention, preservative compatibility, and packaging compatibility through complete stability testing.
Protective Packaging
Use airless, opaque, or UV-protective packaging for premium antioxidant formulations where appropriate.
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Related Documents
Technical Support Materials
COA Document
Get For FreeTDS (Technical Data Sheet)
Get For FreeMSDS (Material Safety Data Sheet)
Get For FreeFormulation Guide
Get For FreeRelated Topics
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Ready to Develop Premium Skincare with Ergothioneine?
Request NOYAIN® Ergothioneine sample, quotation, COA, TDS, MSDS, or formulation support for your next OEM/ODM skincare project.
Frequently Asked Questions
Questions from Formulators and Buyers
- What is Ergothioneine used for in cosmetic formulations?
Ergothioneine is used as an antioxidant and skin-conditioning active in cosmetic formulations. It is suitable for anti-aging serums, urban defense skincare, eye care, after-sun care, sensitive-skin moisturizers, and premium antioxidant product lines.
- Why do brands choose Ergothioneine for skincare products?
Brands choose Ergothioneine because it offers a differentiated antioxidant story beyond general free-radical protection. Its OCTN1 / SLC22A4 cellular uptake narrative supports premium positioning for anti-aging, skin resilience, and environmental stress care formulas.
- What types of products are suitable for Ergothioneine?
Ergothioneine can be used in serums, essences, toners, gel creams, creams, lotions, eye care products, masks, after-sun formulas, and antioxidant day-care systems. It is especially suitable for leave-on skincare products with premium active positioning.
- What is the recommended use level of Ergothioneine?
A typical cosmetic reference range is 0.01%–0.5%. The final use level should be confirmed through formulation compatibility, stability testing, safety assessment, claim support, and target-market compliance review.
- Is Ergothioneine suitable for OEM/ODM skincare projects?
Yes. Ergothioneine is suitable for OEM/ODM projects focused on antioxidant care, anti-aging, urban defense, sensitive-skin comfort, photoaging appearance support, and premium skincare differentiation.
- Can Ergothioneine be combined with other active ingredients?
Yes. Ergothioneine can be used with vitamin C derivatives, niacinamide, ferulic acid, tocopherol, CoQ10, peptides, hyaluronic acid, panthenol, beta-glucan, bisabolol, ceramides, and squalane. Final compatibility should be verified in the complete formula.
- Is Ergothioneine suitable for sensitive-skin formulations?
Yes. Ergothioneine can be used in well-designed sensitive-skin and redness-prone formulas. It works well with soothing and barrier-support ingredients such as panthenol, beta-glucan, bisabolol, allantoin, ceramides, and squalane.