
Preservative System
NA40 | Advanced Acne Care Active Ingredient
An advanced encapsulated salicylic acid complex designed for acne care, oil control, pore refinement, and gentle exfoliation. The cyclodextrin delivery system helps improve stability, reduce irritation, and provide sustained release performance for modern skincare formulations.
INCI
Salicylic Acid / Methyl Cyclodextrin
CAS
69-72-7 / 128446-36-6
Applications
Skincare, Brightening Care, Sun Care
Shelf Life
24 Months
Product Overview
Advanced Encapsulated Salicylic Acid for Acne-Prone Skin
NA40 is an innovative cosmetic active ingredient that combines Salicylic Acid with Methyl Cyclodextrin technology to enhance ingredient delivery and improve formulation performance.
By encapsulating Salicylic Acid within a cyclodextrin carrier, NA40 provides controlled release and improved stability while minimizing the irritation commonly associated with traditional salicylic acid treatments. This advanced delivery system helps maintain effective exfoliation and pore-clearing activity over an extended period.
NA40 is particularly suitable for formulations targeting acne-prone, oily, and congested skin. It supports clearer-looking skin by helping remove excess sebum, reducing pore blockage, and improving overall skin texture.
Its excellent compatibility with various skincare systems makes it suitable for serums, gels, creams, toners, masks, spot treatments, and scalp care products.

Core Advantages
Why Formulators Choose NA40
Controlled Release Technology
Cyclodextrin encapsulation enables gradual release of Salicylic Acid, helping maintain long-lasting efficacy while reducing irritation potential.
Acne Care Support
Helps minimize pore blockage and supports clearer-looking skin prone to blemishes and breakouts.
Oil Control Performance
Assists in reducing excess sebum accumulation and improving skin balance for oily and combination skin types.
Gentle Exfoliation
Promotes removal of dead skin cells and improves skin smoothness without aggressive exfoliation.
Technical Specifications
Product Technical Parameters
Parameter | Specification |
|---|---|
Product Name | NA40 |
INCI Name | Salicylic Acid (and) Methyl Cyclodextrin |
Appearance | White to Off-White Powder |
Purity | 99% |
Recommended Dosage | 0.5% – 5.0% |
Solubility | Dispersible in Water Systems |
pH Stability | 3.5 – 7.0 |
Application | Acne Serums, Spot Treatments, Cleansing Products, Toners, Creams, Gels, Scalp Care Products |
Shelf Life | 24 Months |
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Related Documents
Technical Support Materials
COA Document
Get For FreeTDS (Technical Data Sheet)
Get For FreeMSDS (Material Safety Data Sheet)
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Frequently Asked Questions
- How does encapsulated Salicylic Acid (NA40) differ from traditional Salicylic Acid?
Encapsulated Salicylic Acid uses Methyl Cyclodextrin as a delivery system, which provides controlled release, improved stability, and reduced skin irritation compared to conventional Salicylic Acid powders or solutions. Traditional Salicylic Acid can be harsh for sensitive or acne-prone skin, causing redness or dryness, while NA40 gradually delivers the active for gentle, long-lasting exfoliation and pore-clearing effects.
- What are the benefits of Cyclodextrin-based delivery systems in skincare?
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Cyclodextrin encapsulation offers multiple advantages for cosmetic formulations:
- Stabilizes Salicylic Acid, preventing degradation from air, heat, or pH changes
- Minimizes irritation, making it suitable for sensitive and compromised skin
- Enables sustained release, extending the acne-fighting and oil-control effects over time
- Improves compatibility with other actives, such as Niacinamide, Zinc PCA, or botanical extracts
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- Can NA40 help reduce acne, blemishes, and excess oil?
Yes. NA40 is designed for acne-prone and oily skin formulations. Its benefits include:
- Reducing excess sebum production and shine
- Minimizing pore congestion and blackheads
- Supporting clearer-looking skin and fewer breakouts
- Providing gentle exfoliation to remove dead skin cells without over-drying
- Is NA40 suitable for sensitive or reactive skin formulations?
Yes. The cyclodextrin encapsulation reduces the irritation potential of Salicylic Acid, making NA40 suitable for:
- Sensitive skin formulations
- Combination skin prone to acne and redness
- Scalp care and anti-dandruff products
- Post-treatment skincare (after chemical peels or dermatological procedures)
- What is the recommended dosage of NA40 in cosmetic formulations?
- Typical concentration ranges from 0.5% to 5.0%, depending on product type and target efficacy.
- Higher concentrations are suitable for spot treatments or intensive acne serums.
- Can be formulated in serums, gels, creams, toners, masks, and scalp care products without compromising stability or skin compatibility.
